CBD Oral Film Khoom Taw Qhia
ODF, lub npe tag nrho yog qhov ncauj disintegrating zaj duab xis.Nov yog hom tshuaj noj tshiab.
Cov neeg muab cov ntaub so ntswg tso rau hauv lub qhov ncauj, nws yuav nqus tau cov qaub ncaug, tawg sai sai, kom lub cev nqus tau nws.
Piv nrog rau lwm cov khoom, cov khoom siv zaj duab xis no muaj cov yam ntxwv ntawm kev nqus sai, nqa tau yooj yim, lub neej txee ntev, thiab tsis tas yuav siv lwm cov kua dej ua ke.
Cov khoom no feem ntau siv tau rau kev lag luam xws li tshuaj, khoom kho mob, zaub mov, thiab cannabis derivatives.
Ob peb lub xyoo dhau los no, txoj kev nyiam mus rau lub tshuab xa tshuaj tshiab tau nce ntxiv los ua kom muaj txiaj ntsig zoo, kev nyab xeeb thiab kev lees paub ntawm tus neeg mob.Raws li kev tshawb nrhiav thiab kev tsim cov tshuaj tshiab yog cov txheej txheem nyuaj, kim thiab siv sijhawm ntev, yog li cov kev hloov pauv tsis ntev los no tau hloov mus rau kev tsim thiab tsim cov tshuaj tshiab tshiab rau cov tshuaj uas twb muaj lawm.Tawm ntawm cov no, cov tshuaj xa tshuaj tau zoo heev ntawm cov yeeb yaj kiab hais lus (ODFs).
Cov yeeb yaj kiab tawg nrawm no muaj qhov zoo tshaj plaws ntawm cov ntsiav tshuaj sai sai vim tias qhov kawg cuam tshuam nrog kev pheej hmoo ntawm txhaws thiab friability.Qhov kev xa tshuaj no muaj ntau qhov zoo dua li cov ntsiav tshuaj sai sai disintegrating.
Ntau txoj hauv kev tau ua haujlwm rau kev tsim ODFs thiab cov kev siv tshuaj hnyav thiab tshuaj tsuag yog nquag siv.Feem ntau, hydrophilic polymers nrog rau lwm cov excipients yog siv los npaj ODFs uas tso cai rau cov yeeb yaj kiab kom tawg sai sai tso cov khoom siv tshuaj nquag (API) hauv vib nas this.Qhov ncauj disintegrating films muaj peev xwm rau kev lag luam thiab kev lag luam exploitation vim hais tias ntawm lawv myriad ntawm cov txiaj ntsim tshaj qhov ncauj disintegrating ntsiav tshuaj.
Txoj kev ntawm qhov ncauj ntawm kev tswj hwm tshuaj yog ib txoj hauv kev nyiam tshaj plaws vim nws yooj yim ntawm kev tswj hwm, tsis muaj kev cuam tshuam, yoog raws, tus neeg mob ua raws thiab kev lees paub.Bioadhesive mucosal dosage forms nrog rau cov ntsiav tshuaj nplaum, gels thiab thaj ua rau thaj yog qhov tshwm sim ntawm kev txhim kho thev naus laus zis.Ntawm ntau hom tshuaj, kev siv cov yeeb yaj kiab polymeric rau kev xa tshuaj rau hauv cov kab noj hniav tau tsim muaj peev xwm zoo nyob rau lub sijhawm tsis ntev los no (Arya li al., 2010).Qhov ncauj disintegrating films (ODFs), thaum muab tso rau ntawm tus nplaig, tam sim ntawd hydrates los ntawm soaking qaub ncaug tom qab disintegration thiab/los yog dissolution tso active tshuaj tus neeg sawv cev los ntawm ntau npaum li cas daim ntawv (Chauhan li al., 2012).ODFs yog hom formulations uas feem ntau npaj siv hydrophilic polymers ua kom sai sai sai thaum sib cuag nrog qaub ncaug.Qhov ncauj disintegrating ntsiav tshuaj (ODTs) thiab qhov ncauj disintegrating films (ODFs) yog cov piv txwv ntawm qhov ncauj disintegrating tshuaj xa systems.
Kev thov ntawm hemp hauv ODF yog nyob rau theem tshiab.Cov tshuaj CBD uas muaj nyob rau hauv txhua zaj duab xis raug kho, thiab cov khoom CBD uas tau noj txhua lub sijhawm kuj raug kho, uas ua kom cov neeg siv yuav tsis noj tshuaj ntau dhau.Nyob rau tib lub sijhawm, qhov cuam tshuam sai sai ua rau cov khoom muaj txiaj ntsig tau sai sai thiab nqus tau.
